CAS 15687-27-1 for Antiinflammatory and Antibiotic /Pharmaceutical Raw Material Ibuprofen
Product Name: Ibuprofen
Synonyms: RARECHEM AL BO 0989;MOTRIN(TM);(+/-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID;2-(4-ISOBUTYLPHENYL)PROPIONIC ACID;4-ISOBUTYL-ALPHA-METHYLPHENYLACETIC ACID;AKOS NCG1-0060
Product Categories: Active Pharmaceutical Ingredients;API;APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Lipid signaling;Isotopically Labeled Pharmaceutical Reference Standard;ADVIL;Other APIs
mp 77-78 °C(lit.)
bp 157 °C (4 mmHg)
storage temp. -20deg;C Freezer
Water Solubility insoluble
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Chemical Properties : Colourless, Crystalline Solid
Usage : A selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency
Anti-inflammatory, analgesic, antipyretic effect. The efficacy of the treatment of rheumatism and rheumatoid arthritis slightly inferior to acetyl salicylic acid and phenylbutazone. Suitable for the treatment of rheumatic arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and neuritis. The product in 1985 America drug sales order in thirteenth.
Appearance:white crystalline powder
Indomethacin is commonly used as a prescription medication to treat fever, analgesic or inflammation caused by many conditions such as arthritis, gout, ankylosing spondylitis, bursitis, rheumatism, or tendinitis.
Indometacin works by reducing the production of prostaglandins, Prostaglandins are chemicals that the body produces and which cause the fever and pain that are associated with inflammation. Indometacin is similar to ibuprofen (Motrin) and naproxen (Naprosyn, Aleve).
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